From AppleGamingWiki, the wiki about gaming on M1 Apple silicon Macs					
									
					
						
				
					
Availability
-  See PCGamingWiki for Windows and/or Linux availability.
macOS Compatibility
macOS Compatibility
		| Method | Rating | Notes | 
		| Native |  |  | 
		| Rosetta 2 |  |  | 
CrossOver
  
    | CrossOver Bottle settings[1] | 
    | Click Bottles iconCtrl + click BottleEnable Settings - Enable Performance Enhanced Synchronization (ESync)Enable Settings - Enable DXVK Backend D3D11
 | 
Audio and voices not working
  
    | Wine configuration Library overrides[2] | 
    | Under Control Panels, double click Wine ConfigurationIn Libraries select 'New override for library'Select each library file and click 'Add'
x3audio1_6x3audio1_7xaudio2_6xaudio2_7
 | 
Mouse locked to screen
  
    | Add bBackgroundMouse=1 to Fallout4.ini[3] | 
    | Find Fallout4.ininormally within\Documents\My Games\Fallout4.iniCtrl + click Fallout4.iniand open with TextEditUnder the [Controls] heading add the line bBackgroundMouse=1Click File and Save
 | 
References